Immune Complexes – Close Encounter of Antigen and Antibody

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About > Immune Complexes > product of antibody binding to antigen.

Designer antibody therapy and antibody design for best capture of analytes in the diagnostic laboratory set the stage for antigen-antibody complexes as illimited scenarios of applications.

Interaction of Immune Complexes with cells and complement taps into the metabolome and effector systems relevant to human pathology, including, at best, the NLRP3 inflammasome system.  Immune Complexes and their receptor lab analytics, including complement system piled up into big data warehouses need to be turned into smart data for the patients – a challenge for primary caretakers cross-examined with this website, immune-complex.ch. In 2019, the four V’s make immune complexes even more thrilling: volume (molecular size), velocity (speed of complex formation between antibody and antigen), variety of information (results from lab tests detecting immune complexes) and value (what does this mean for the patient). Glycation extent of immunoglobulins and whether they are also classified as AGE (advanced glycation end products) in senescence is currently scrutinized.
Fc fragments undergoing sialylation and fucosylation to different extents do change functional performance of the IgG in immune defense.

 

Autobiography

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Lab test Reference Intervals

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update january 2020 

Webmasters’ Urs E. Nydeggers’ Profile Worpress Teaching Bern (Switzerland) on january 23, 2020