Immune Complexes – Close Encounter of Antigen and Antibody

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About > Immune Complexes > product of antibody binding to antigen.

Designer antibody therapy and antibody design for best capture of analytes in the diagnostic laboratory set the stage for antigen-antibody complexes as illimited scenarios of applications.

Interaction of Immune Complexes with cells and complement taps into so far unknown sites and effector systems relevant to human pathology, including, at its very best, the NLRP3 inflammasome system.  Immune Complexes and their receptor lab analytics, including complement system piled up into big data warehouses need to be turned into smart data for the patients – a challenge for primary caretakers cross-examined with this website, immune-complex.ch. In 2019, the four V’s make immune complexes even more thrilling: volume (molecular size), velocity (speed of complex formation between antibody and antigen), variety of information (results from lab tests detecting immune complexes) and value (what does this mean for the patient). We will soon dwell into glycation extent of immunoglobulins and whether they are also subject to be classified as AGE (advanced glycation end products) in senescence. Keep track when coming home from Florence (Italy) as look back from the  5th International Congress on ‘Controversies in Rheumatology & Autoimmunity 2019’ (http://cora.kenes.com). We will reckon the topic in the context of rheumatoid diseases and seamlessly coordinate with the mosaic of autoimmune diseases.

 

 

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update February  2019 

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