Clustered regularly interspaced short palindromic repeats (CRISPRs) are groups of identical repeated DNA sequences which can act with associated genes (Cas) to confer innate immunity to bacteria against foreign intruders. For the time being we do not yet sense a relation of CRISPR Cas9 to diagnosing or treating immune complex disease but the day may not be far away we will learn that such a relation could be explored.
New approaches using CRISPR in fact do not edit genes directly, but the scissors are used to prevent genes from being expressed: gene-silencing therapy  – ref [61] from our recent review in the Journal of Translational Autoimmunity (2021).