Clustered regularly interspaced short palindromic repeats (CRISPRs) are groups of identical repeated DNA sequences which can act with associated genes (Cas) to confer innate immunity to bacteria against foreign intruders. For the time being we do not yet sense a relation of CRISPR Cas9 to diagnosing or treating immune complex disease but the day may not be far away we will learn that such a relation could be explored.
We are currently (february 2020) assembling the program of the Bernese Laboratory Conferences 2020 the program of which might shed light on this. Human Genome Editing (HGE) might give the clue.