Red blood cells are not solely transporting oxygen!
We here can see that they carry an immune complex according to the depicted scheme (out of scale). Owuor BO et al showed in 2008 that reduced immune complex binding capacity and increased complement susceptibility of RBCs from children with severe malaria is associated with anemia. This brings the RBC function to the point: deficiencies in RBC CR1 and CD55 in children with severe malaria associated anemia were accompanied by a marked decline in IC binding capacity and increased C3b deposition in vivo and ex vivo
Mol Med 2008;14(3-4):89-97